{"id":1034,"date":"2023-02-09T15:13:24","date_gmt":"2023-02-09T06:13:24","guid":{"rendered":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/?post_type=example&p=1034"},"modified":"2023-02-09T15:13:24","modified_gmt":"2023-02-09T06:13:24","slug":"%e8%aa%8d%e7%9f%a5%e6%a9%9f%e8%83%bd%e3%82%92%e6%8b%85%e3%81%86%e8%84%b3%e3%81%ae%e9%81%ba%e4%bc%9d%e5%ad%90%e3%83%bb%e5%88%86%e5%ad%90%e5%9f%ba%e7%9b%a4%e3%81%ae%e8%a7%a3%e6%98%8e%e3%81%a8-%e6%a9%9f","status":"publish","type":"example","link":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/en\/example\/1034\/","title":{"rendered":"To elucidate the genetic and molecular basis of the brain for cognitive function and to discover drugs for the improvement of this function."},"featured_media":0,"parent":0,"template":"","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","vkexunit_cta_each_option":""},"city":[],"class_list":["post-1034","example","type-example","status-publish","hentry","en-US"],"acf":{"exam_dept":[969],"exam_name":"Graduate School of Medical and Dental Sciences \r\nAdvanced Therapeutics Course\r\nFunctional Biology and Pharmacology \r\nProfessor\r\nOKUNO Hiroyuki","exam_overview_img":"","exam_person":"","exam_overview_caption":"","exam_access":[{"exam_access_url":"https:\/\/www2.kufm.kagoshima-u.ac.jp\/field\/advanced-therapeutics\/f105\/02.html"},{"exam_access_url":"https:\/\/www.kufm.kagoshima-u.ac.jp\/~biochem2\/"}],"exam_objective":"03","exam_purpose":{"exam_purpose_text":"It remains important to maintain brain health throughout one's life in order to lead a peaceful and happy life. Overcoming dementia and other higher brain dysfunctions is an urgent issue in today's aging society, and treatments for recovery from and alleviation of developmental disorders such as autistic spectrum disorder are desired. In this study, we will clarify the molecular mechanisms of cognitive functions by analyzing the roles of genes and molecules involved in cognitive functions in the cerebrum. It will also lead to the development of drug discovery and treatment methods.","exam_purpose_img":"","exam_purpose_caption":""},"exam_overview":{"exam_overview_text":"The brain's function is thought to be based on synapses, which are the smallest units at which information is exchanged between neurons. In this study, we will use the latest molecular biology techniques (genome editing and developmental engineering) to clarify the functions of genes and molecules that support synaptic function. We are also developing drugs that target these genes and molecules and modulate synaptic function in collaboration with pharmaceutical companies.","exam_overview_img":658,"exam_overview_caption":"\u57f9\u990a\u795e\u7d4c\u7d30\u80de\u306e\u30b7\u30ca\u30d7\u30b9\u5206\u5e03 \uff08\u30de\u30bc\u30f3\u30bf\u306fPSD-95\u3001\u7dd1\u306fvGlut1\u3068\u3044\u3046\u30b7\u30ca\u30d7\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u8868\u3057\u307e\u3059\uff09"},"exam_effect":"The clarification of the molecular basis of synaptic function and the establishment of methods for its regulation will greatly advance the development of treatments and therapeutics for various brain dysfunctions such as dementia, psychiatric disorders, and developmental disorders.","exam_site":[{"exam_site_name":"\"Graduate School of Medical and Dental Sciences Website (Introduction of Laboratories) \"","exam_site_url":"https:\/\/www2.kufm.kagoshima-u.ac.jp\/field\/advanced-therapeutics\/f105\/02.html"},{"exam_site_name":"Field site","exam_site_url":"https:\/\/www.kufm.kagoshima-u.ac.jp\/~biochem2\/"},{"exam_site_name":"Elucidating memory mechanisms at the molecular level\uff08 Kagoshima University Industry-Academia-Regional Co-Creation Center Website\uff09","exam_site_url":"https:\/\/seeds.krcc.kagoshima-u.ac.jp\/seeds_info\/pdf\/30-Ls-okuno-med.pdf"},{"exam_site_name":"Kagoshima University Homepage Straight line of research","exam_site_url":"https:\/\/www.kagoshima-u.ac.jp\/researcher\/"}],"exam_impact2023":"","exam_remarks":""},"_links":{"self":[{"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/example\/1034","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/example"}],"about":[{"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/types\/example"}],"version-history":[{"count":0,"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/example\/1034\/revisions"}],"acf:post":[{"embeddable":true,"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/department\/969"}],"wp:attachment":[{"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/media?parent=1034"}],"wp:term":[{"taxonomy":"city","embeddable":true,"href":"https:\/\/sdgs.kuas.kagoshima-u.ac.jp\/wp-json\/wp\/v2\/city?post=1034"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}